6MUX

The structure of the Plasmodium falciparum 20S proteasome in complex with one PA28 activator

Summary for 6MUX

Entry DOI	10.2210/pdb6mux/pdb
Related	6DFK 6MUV 6MUW
EMDB information	9257 9258 9259
Descriptor	20S proteasome alpha-1 subunit, 20S proteasome beta-3 subunit, 20S proteasome beta-4 subunit, ... (15 entities in total)
Functional Keywords	proteasome, protease, hydrolase, 11s subunit, hydrolyse activator, proteasome activator, complex
Biological source	Plasmodium falciparum 3D7 More
Total number of polymer chains	35
Total formula weight	995141.72
Authors	Metcalfe, R.D.,Xie, S.C.,Hanssen, E.,Gillett, D.L.,Leis, A.P.,Tilley, L.,Griffin, M.D.W. (deposition date: 2018-10-23, release date: 2019-08-07, Last modification date: 2024-03-13)
Primary citation	Xie, S.C.,Metcalfe, R.D.,Hanssen, E.,Yang, T.,Gillett, D.L.,Leis, A.P.,Morton, C.J.,Kuiper, M.J.,Parker, M.W.,Spillman, N.J.,Wong, W.,Tsu, C.,Dick, L.R.,Griffin, M.D.W.,Tilley, L. The structure of the PA28-20S proteasome complex from Plasmodium falciparum and implications for proteostasis. Nat Microbiol, 4:1990-2000, 2019 Cited by PubMed: 31384003 DOI: 10.1038/s41564-019-0524-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation