6MOJ

Dimeric DARPin A_angle_R5 complex with EpoR

Summary for 6MOJ

Entry DOI	10.2210/pdb6moj/pdb
Descriptor	Dimeric DARPin ACR5 (A_angle_R5), Erythropoietin receptor, D(-)-TARTARIC ACID, ... (5 entities in total)
Functional Keywords	darpin, complex, receptor, biosynthetic protein
Biological source	synthetic construct More
Total number of polymer chains	2
Total formula weight	50117.64
Authors	Jude, K.M.,Mohan, K.,Garcia, K.C. (deposition date: 2018-10-04, release date: 2019-06-05, Last modification date: 2023-10-11)
Primary citation	Mohan, K.,Ueda, G.,Kim, A.R.,Jude, K.M.,Fallas, J.A.,Guo, Y.,Hafer, M.,Miao, Y.,Saxton, R.A.,Piehler, J.,Sankaran, V.G.,Baker, D.,Garcia, K.C. Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364:-, 2019 Cited by PubMed: 31123111 DOI: 10.1126/science.aav7532 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.431 Å)

Structure validation