6K06

Crystal structure of Importin-alpha and phosphomimetic GM130

Summary for 6K06

Entry DOI	10.2210/pdb6k06/pdb
Descriptor	Peptide from Golgin subfamily A member 2, Importin subunit alpha-1 (3 entities in total)
Functional Keywords	importin alpha, gm130, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	52696.28
Authors	Chang, C.-C.,Chen, C.-J.,Pien, Y.-C.,Tsai, S.-Y.,Hsia, K.-C. (deposition date: 2019-05-05, release date: 2019-10-02, Last modification date: 2023-11-22)
Primary citation	Chang, C.-C.,Chen, C.-J.,Grauffel, C.,Pien, Y.-C.,Lim, C.,Tsai, S.-Y.,Hsia, K.-C. Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10:4307-4307, 2019 Cited by PubMed: 31541088 DOI: 10.1038/s41467-019-12207-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation