6HVC

NMR structure of Urotensin Peptide Asp-c[Cys-Phe-Trp-(N-Me)Lys-Tyr-Cys]-Val in SDS solution

Summary for 6HVC

• Entry DOI: 10.2210/pdb6hvc/pdb
• NMR Information: BMRB: 34319
• Descriptor: Urotensin-2 (1 entity in total)
• Functional Keywords: g protein-coupled receptor, urotensin ii receptor, nmr solutions, sds, n-methylation, peptide binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 1078.28

Authors

Brancaccio, D.,Carotenuto, A.,Merlino, F.,Billard, E.,Yousif, A.M.,Di Maro, S.,Abate, L.,Bellavita, R.,D'Emmanuele di Villa Bianca, R.,Santicioli, P.,Marinelli, L.,Novellino, E.,Hebert, T.E.,Lubell, W.D.,Chatenet, D.,Grieco, P. (deposition date: 2018-10-10, release date: 2019-01-16, Last modification date: 2019-04-24)

• Primary citation: Merlino, F.,Billard, E.,Yousif, A.M.,Di Maro, S.,Brancaccio, D.,Abate, L.,Carotenuto, A.,Bellavita, R.,d'Emmanuele di Villa Bianca, R.,Santicioli, P.,Marinelli, L.,Novellino, E.,Hebert, T.E.,Lubell, W.D.,Chatenet, D.,Grieco, P.; Functional Selectivity Revealed by N-Methylation Scanning of Human Urotensin II and Related Peptides.; J.Med.Chem., 62:1455-1467, 2019; PubMed: 30615452; DOI: 10.1021/acs.jmedchem.8b01601

Experimental method

SOLUTION NMR