6HLQ

Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP

Summary for 6HLQ

• Entry DOI: 10.2210/pdb6hlq/pdb
• EMDB information: 0238 0239
• Descriptor: DNA-directed RNA polymerase I subunit RPA190, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, ... (18 entities in total)
• Functional Keywords: transcription, polymerase, nucleotide, elongation
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 15
• Total formula weight: 547427.68

Authors

Tafur, L.,Sadian, Y.,Weis, F.,Muller, C.W. (deposition date: 2018-09-11, release date: 2019-04-03, Last modification date: 2019-12-18)

• Primary citation: Tafur, L.,Sadian, Y.,Hanske, J.,Wetzel, R.,Weis, F.,Muller, C.W.; The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.; Elife, 8:-, 2019; PubMed: 30913026; DOI: 10.7554/eLife.43204

Experimental method

ELECTRON MICROSCOPY (3.18 Å)