6HJD

Cholera toxin classical B-pentamer in complex with Lewis-x

Summary for 6HJD

• Entry DOI: 10.2210/pdb6hjd/pdb
• Related: 5ELB 5ELD
• Related PRD ID: PRD_900119 PRD_900120
• Descriptor: Cholera toxin B subunit, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: toxin, cholera toxin, lectin, complex, lewis-x, protein-carbohydrate interactions, x-ray crystal structure
• Biological source: Vibrio cholerae
• Total number of polymer chains: 10
• Total formula weight: 122665.25

Authors

Krengel, U.,Heim, J.B. (deposition date: 2018-09-03, release date: 2019-08-14, Last modification date: 2024-01-17)

• Primary citation: Heim, J.B.,Hodnik, V.,Heggelund, J.E.,Anderluh, G.,Krengel, U.; Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.; Sci Rep, 9:12243-12243, 2019; PubMed: 31439922; DOI: 10.1038/s41598-019-48579-2

Experimental method

X-RAY DIFFRACTION (1.54 Å)