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6HHQ

Crystal structure of compound C45 bound to the yeast 80S ribosome

This is a non-PDB format compatible entry.
Summary for 6HHQ
Entry DOI10.2210/pdb6hhq/pdb
Descriptor25S ribosomal RNA, 60S ribosomal protein L8-A, 60S ribosomal protein L9-A, ... (86 entities in total)
Functional Keywords80s ribosome, inhibitor, anti-cancer, ribosome
Biological sourceSaccharomyces cerevisiae
More
Total number of polymer chains159
Total formula weight6646164.98
Authors
Pellegrino, S.,Vanderwal, C.D.,Yusupov, M. (deposition date: 2018-08-28, release date: 2019-02-20, Last modification date: 2019-04-17)
Primary citationPellegrino, S.,Meyer, M.,Konst, Z.A.,Holm, M.,Voora, V.K.,Kashinskaya, D.,Zanette, C.,Mobley, D.L.,Yusupova, G.,Vanderwal, C.D.,Blanchard, S.C.,Yusupov, M.
Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47:3223-3232, 2019
Cited by
PubMed: 30759226
DOI: 10.1093/nar/gkz053
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.10000049683 Å)
Structure validation

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