6GR9

Human AURKC INCENP complex bound to VX-680

Summary for 6GR9

• Entry DOI: 10.2210/pdb6gr9/pdb
• Descriptor: Aurora kinase C, Inner centromere protein, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, ... (5 entities in total)
• Functional Keywords: kinase, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 41030.15

Authors

Abdul Azeez, K.R.,Sorrell, F.J.,von Delft, F.,Bountra, C.,Knapp, S.,Edwards, A.M.,Arrowsmith, C.,Elkins, J.M. (deposition date: 2018-06-10, release date: 2019-05-15, Last modification date: 2024-01-17)

• Primary citation: Abdul Azeez, K.R.,Elkins, J.M.; AURKC INCENP complex bound to BRD-7880; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)