6GE4

TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100) AND MYRISTOATE (COVALENTLY BOUND) AT 1.97A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA

Summary for 6GE4

• Entry DOI: 10.2210/pdb6ge4/pdb
• Related: 6GE3
• Descriptor: Transcriptional enhancer factor TEF-3, Transcriptional coactivator YAP1, MYRISTIC ACID, ... (4 entities in total)
• Functional Keywords: transcription, co-activator, protein-protein interaction
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30321.37

Authors

Kallen, J. (deposition date: 2018-04-25, release date: 2018-09-19, Last modification date: 2024-01-17)

• Primary citation: Mesrouze, Y.,Bokhovchuk, F.,Izaac, A.,Meyerhofer, M.,Zimmermann, C.,Fontana, P.,Schmelzle, T.,Erdmann, D.,Furet, P.,Kallen, J.,Chene, P.; Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.; Protein Sci., 27:1810-1820, 2018; PubMed: 30058229; DOI: 10.1002/pro.3493

Experimental method

X-RAY DIFFRACTION (1.97 Å)