6GCH

STRUCTURE OF CHYMOTRYPSIN-*TRIFLUOROMETHYL KETONE INHIBITOR COMPLEXES. COMPARISON OF SLOWLY AND RAPIDLY EQUILIBRATING INHIBITORS

6GCH の概要

• エントリーDOI: 10.2210/pdb6gch/pdb
• 分子名称: GAMMA-CHYMOTRYPSIN A, 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE), ... (5 entities in total)
• 機能のキーワード: hydrolase (serine proteinase)
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Secreted, extracellular space: P00766 P00766 P00766
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 25521.79

構造登録者

Brady, K.,Wei, A.,Ringe, D.,Abeles, R.H. (登録日: 1990-04-06, 公開日: 1990-10-15, 最終更新日: 2011-07-13)

• 主引用文献: Brady, K.,Wei, A.Z.,Ringe, D.,Abeles, R.H.; Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors.; Biochemistry, 29:7600-7607, 1990; PubMed: 2271520; DOI: 10.1021/bi00485a009

実験手法

X-RAY DIFFRACTION (2.1 Å)