6DHM
Bovine glutamate dehydrogenase complexed with zinc
Replaces: 3MVQReplaces: 1CH6Replaces: 1HWXReplaces: 3MW9Summary for 6DHM
Entry DOI | 10.2210/pdb6dhm/pdb |
Descriptor | Glutamate dehydrogenase 1, mitochondrial, GLUTAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | glutamate, dehydrogenase, zinc, inhibition, oxidoreductase |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 6 |
Total formula weight | 392227.48 |
Authors | Smith, T.J. (deposition date: 2018-05-20, release date: 2018-07-25, Last modification date: 2024-03-13) |
Primary citation | Bailey, J.,Powell, L.,Sinanan, L.,Neal, J.,Li, M.,Smith, T.,Bell, E. A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis. FEBS J., 278:3140-3151, 2011 Cited by PubMed: 21749647DOI: 10.1111/j.1742-4658.2011.08240.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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