6D8C

Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin

Summary for 6D8C

Entry DOI	10.2210/pdb6d8c/pdb
EMDB information	7831 7832 7833
Related PRD ID	PRD_002307
Descriptor	Filamin-A, Actin, alpha skeletal muscle, Phalloidin, ... (5 entities in total)
Functional Keywords	actin-binding domain, actin crosslinker, structural protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	13
Total formula weight	386378.54
Authors	Iwamoto, D.V.,Huehn, A.R.,Simon, B.,Huet-Calderwood, C.,Baldassarre, M.,Sindelar, C.V.,Calderwood, D.A. (deposition date: 2018-04-26, release date: 2018-09-19, Last modification date: 2023-11-15)
Primary citation	Iwamoto, D.V.,Huehn, A.,Simon, B.,Huet-Calderwood, C.,Baldassarre, M.,Sindelar, C.V.,Calderwood, D.A. Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat. Struct. Mol. Biol., 25:918-927, 2018 Cited by PubMed: 30224736 DOI: 10.1038/s41594-018-0128-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.54 Å)

Structure validation