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6CUG

Crystal structure of BC8B TCR-CD1b-PC complex

Summary for 6CUG
Entry DOI10.2210/pdb6cug/pdb
DescriptorT-cell surface glycoprotein CD1b, Beta-2-microglobulin, T-cell receptor alpha variable TRAV9-2 - BC8B TCR, ... (9 entities in total)
Functional Keywordst cell receptor, antigen presenting molecule, cd1b, pc, phosphatidylcholine, immune system
Biological sourceHomo sapiens (Human)
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Total number of polymer chains4
Total formula weight97241.68
Authors
Shahine, A.E.,Rossjohn, J. (deposition date: 2018-03-26, release date: 2019-01-16, Last modification date: 2023-10-04)
Primary citationShahine, A.,Reinink, P.,Reijneveld, J.F.,Gras, S.,Holzheimer, M.,Cheng, T.Y.,Minnaard, A.J.,Altman, J.D.,Lenz, S.,Prandi, J.,Kubler-Kielb, J.,Moody, D.B.,Rossjohn, J.,Van Rhijn, I.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10:56-56, 2019
Cited by
PubMed: 30610190
DOI: 10.1038/s41467-018-07898-0
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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