6CFP
CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE
Summary for 6CFP
Entry DOI | 10.2210/pdb6cfp/pdb |
Descriptor | Ubiquitin-like protein SMT3,Polymerase acidic protein, 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | influenza, h1n1, fragment-based drug discovery, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 1 |
Total formula weight | 64454.60 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-02-15, release date: 2018-04-11, Last modification date: 2023-10-04) |
Primary citation | Seattle Structural Genomics Center for Infectious Disease (SSGCID),Davies, D.R.,Abendroth, J.,Lorimer, D.,Horanyi, P.S.,Edwards, T.E. CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
Download full validation report