6CFL

Crystal structure of the Thermus thermophilus 70S ribosome in complex with lysyl-CAM and bound to protein Y (YfiA) at 2.6A resolution

This is a non-PDB format compatible entry.

Summary for 6CFL

• Entry DOI: 10.2210/pdb6cfl/pdb
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (61 entities in total)
• Functional Keywords: chloramphenicol, antibiotic, inhibitor, ribosome, 70s, ribosome structure, inhibition of translation, peptidyl transferase center, ribosome-inhibitor complex, ribosome/inhibitor
• Biological source: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579); More
• Total number of polymer chains: 106
• Total formula weight: 4425057.66

Authors

Tereshchenkov, A.G.,Dobosz-Bartoszek, M.,Osterman, I.A.,Marks, J.,Sergeeva, V.A.,Kasatsky, P.,Komarova, E.S.,Stavrianidi, A.N.,Rodin, I.A.,Konevega, A.L.,Sergiev, P.V.,Sumbatyan, N.V.,Mankin, A.S.,Bogdanov, A.A.,Polikanov, Y.S. (deposition date: 2018-02-15, release date: 2018-03-07, Last modification date: 2023-11-15)

• Primary citation: Tereshchenkov, A.G.,Dobosz-Bartoszek, M.,Osterman, I.A.,Marks, J.,Sergeeva, V.A.,Kasatsky, P.,Komarova, E.S.,Stavrianidi, A.N.,Rodin, I.A.,Konevega, A.L.,Sergiev, P.V.,Sumbatyan, N.V.,Mankin, A.S.,Bogdanov, A.A.,Polikanov, Y.S.; Binding and Action of Amino Acid Analogs of Chloramphenicol upon the Bacterial Ribosome.; J. Mol. Biol., 430:842-852, 2018; PubMed: 29410130; DOI: 10.1016/j.jmb.2018.01.016

Experimental method

X-RAY DIFFRACTION (2.6 Å)