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6C98

Crystal structure of FcRn bound to UCB-84

Summary for 6C98
Entry DOI10.2210/pdb6c98/pdb
DescriptorIgG receptor FcRn large subunit p51, Beta-2-microglobulin, CYSTEINE, ... (7 entities in total)
Functional Keywordsneonatal fc receptor, fcrn, inhibitor, beta 2 microglobulin, b2m, immune system
Biological sourceHomo sapiens (Human)
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Cellular locationCell membrane ; Single-pass type I membrane protein : P55899
Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains4
Total formula weight85385.68
Authors
Fox III, D.,Lukacs, C.M. (deposition date: 2018-01-25, release date: 2018-05-30)
Primary citationStoppler, D.,Macpherson, A.,Smith-Penzel, S.,Basse, N.,Lecomte, F.,Deboves, H.,Taylor, R.D.,Norman, T.,Porter, J.,Waters, L.C.,Westwood, M.,Cossins, B.,Cain, K.,White, J.,Griffin, R.,Prosser, C.,Kelm, S.,Sullivan, A.H.,Fox, D.,Carr, M.D.,Henry, A.,Taylor, R.,Meier, B.H.,Oschkinat, H.,Lawson, A.D.
Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16:e2006192-e2006192, 2018
Cited by
PubMed: 29782488
DOI: 10.1371/journal.pbio.2006192
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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