6BZ3

Complex structure of FAK FAT domain and DCC P3 motif

Summary for 6BZ3

Entry DOI	10.2210/pdb6bz3/pdb
Descriptor	Focal adhesion kinase 1, Netrin receptor DCC, CALCIUM ION, ... (4 entities in total)
Functional Keywords	4-helix bundle, axon guidance, focal adhesion kinase, transferase-peptide complex, membrane protein, transferase-membrane protein complex, transferase/membrane protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	4
Total formula weight	32958.32
Authors	Xu, S.,Wang, J.-H. (deposition date: 2017-12-22, release date: 2018-04-04, Last modification date: 2023-10-04)
Primary citation	Xu, S.,Liu, Y.,Li, X.,Liu, Y.,Meijers, R.,Zhang, Y.,Wang, J.H. The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction. Cell Discov, 4:8-8, 2018 Cited by PubMed: 29479476 DOI: 10.1038/s41421-017-0008-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.497 Å)

Structure validation