6BQ1

Human PI4KIIIa lipid kinase complex

Summary for 6BQ1

Entry DOI	10.2210/pdb6bq1/pdb
EMDB information	7129
Descriptor	Phosphatidylinositol 4-kinase III alpha (PI4KA), Tetratricopeptide repeat protein 7B, Protein FAM126A, ... (5 entities in total)
Functional Keywords	kinase, phosphoinositide synthesis, transferase-signaling protein complex, transferase/signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	607175.40
Authors	Lees, J.A.,Zhang, Y.,Oh, M.,Schauder, C.M.,Yu, X.,Baskin, J.,Dobbs, K.,Notarangelo, L.D.,Camilli, P.D.,Walz, T.,Reinisch, K.M. (deposition date: 2017-11-27, release date: 2017-12-13, Last modification date: 2024-03-13)
Primary citation	Lees, J.A.,Zhang, Y.,Oh, M.S.,Schauder, C.M.,Yu, X.,Baskin, J.M.,Dobbs, K.,Notarangelo, L.D.,De Camilli, P.,Walz, T.,Reinisch, K.M. Architecture of the human PI4KIII alpha lipid kinase complex. Proc. Natl. Acad. Sci. U.S.A., 114:13720-13725, 2017 Cited by PubMed: 29229838 DOI: 10.1073/pnas.1718471115 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation