6BJD
Crystal Structure of Human Calpain-3 Protease Core in Complex with E-64
Summary for 6BJD
| Entry DOI | 10.2210/pdb6bjd/pdb |
| Related | 6BDT |
| Descriptor | Calpain-3, CALCIUM ION, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | calcium binding, cysteine protease, calpain, p94, complex, e-64, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 179911.03 |
| Authors | Ye, Q.,Campbell, R.L.,Davies, P.L. (deposition date: 2017-11-06, release date: 2018-02-07, Last modification date: 2023-10-04) |
| Primary citation | Ye, Q.,Campbell, R.L.,Davies, P.L. Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation. J. Biol. Chem., 293:4056-4070, 2018 Cited by PubMed: 29382717DOI: 10.1074/jbc.RA117.001097 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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