6BC1
A Complex between PH Domain of p190RhoGEF and Activated Rac1 Bound to a GTP Analog
Summary for 6BC1
Entry DOI | 10.2210/pdb6bc1/pdb |
Descriptor | Ras-related C3 botulinum toxin substrate 1, Rho guanine nucleotide exchange factor 28, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (5 entities in total) |
Functional Keywords | rho gtpase guanine nucleotide exchange factors rhogef pleckstrin homology ph domain, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 77204.57 |
Authors | Chen, Z.,Sternweis, P.C. (deposition date: 2017-10-20, release date: 2017-12-13, Last modification date: 2024-03-13) |
Primary citation | Dada, O.,Gutowski, S.,Brautigam, C.A.,Chen, Z.,Sternweis, P.C. Direct regulation of p190RhoGEF by activated Rho and Rac GTPases. J. Struct. Biol., 202:13-24, 2018 Cited by PubMed: 29196061DOI: 10.1016/j.jsb.2017.11.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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