6B42

Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) 2'-deoxy-AMP complex at 1.13A resolution

Replaces:  5KM7

Summary for 6B42

• Entry DOI: 10.2210/pdb6b42/pdb
• Descriptor: Histidine triad nucleotide-binding protein 1, 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: hint, histidine triad, hit, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14427.41

Authors

Maize, K.M.,Finzel, B.C. (deposition date: 2017-09-25, release date: 2017-10-18, Last modification date: 2023-10-04)

• Primary citation: Maize, K.M.,Shah, R.,Strom, A.,Kumarapperuma, S.,Zhou, A.,Wagner, C.R.,Finzel, B.C.; A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.; Mol. Pharm., 14:3987-3997, 2017; PubMed: 28968488; DOI: 10.1021/acs.molpharmaceut.7b00664

Experimental method

X-RAY DIFFRACTION (1.13 Å)