6APX

Crystal structure of human dual specificity phosphatase 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the monobody YSX1

Summary for 6APX

Entry DOI	10.2210/pdb6apx/pdb
Descriptor	Maltose-binding periplasmic protein,Dual specificity protein phosphatase 1, Monobody YSX1, SULFATE ION, ... (5 entities in total)
Functional Keywords	dual specificity phosphatase, dusp, c258s, hydrolase
Biological source	Escherichia coli (strain K12) More
Cellular location	Nucleus : P28562
Total number of polymer chains	2
Total formula weight	67899.48
Authors	Gumpena, R.,Lountos, G.T.,Sreejith, R.K.,Tropea, J.E.,Cherry, S.,Waugh, D.S. (deposition date: 2017-08-18, release date: 2017-11-01, Last modification date: 2023-10-04)
Primary citation	Gumpena, R.,Lountos, G.T.,Raran-Kurussi, S.,Tropea, J.E.,Cherry, S.,Waugh, D.S. Crystal structure of the human dual specificity phosphatase 1 catalytic domain. Protein Sci., 27:561-567, 2018 Cited by PubMed: 29052270 DOI: 10.1002/pro.3328 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.491 Å)

Structure validation