5YDR

Structure of DNMT1 RFTS domain in complex with ubiquitin

Summary for 5YDR

• Entry DOI: 10.2210/pdb5ydr/pdb
• Descriptor: Polyubiquitin-B, DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: dna methylation, protein binding, protein binding-transferase complex, protein binding/transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus : P26358
• Total number of polymer chains: 3
• Total formula weight: 45239.20

Authors

Qian, C. (deposition date: 2017-09-14, release date: 2018-02-21, Last modification date: 2023-11-22)

• Primary citation: Li, T.,Wang, L.,Du, Y.,Xie, S.,Yang, X.,Lian, F.,Zhou, Z.,Qian, C.; Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.; Nucleic Acids Res., 46:3218-3231, 2018; PubMed: 29471350; DOI: 10.1093/nar/gky104

Experimental method

X-RAY DIFFRACTION (2.003 Å)