5Y0D
Crystal Structure of the human nucleosome containing the H2B E76K mutant
Summary for 5Y0D
Entry DOI | 10.2210/pdb5y0d/pdb |
Descriptor | Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (8 entities in total) |
Functional Keywords | dna binding, nucleus, histone fold, chromatin formation, nucleosome, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 202922.01 |
Authors | Kurumizaka, H.,Arimura, Y.,Fujita, R.,Noda, M. (deposition date: 2017-07-16, release date: 2018-07-18, Last modification date: 2023-11-22) |
Primary citation | Arimura, Y.,Ikura, M.,Fujita, R.,Noda, M.,Kobayashi, W.,Horikoshi, N.,Sun, J.,Shi, L.,Kusakabe, M.,Harata, M.,Ohkawa, Y.,Tashiro, S.,Kimura, H.,Ikura, T.,Kurumizaka, H. Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome. Nucleic Acids Res., 46:10007-10018, 2018 Cited by PubMed: 30053102DOI: 10.1093/nar/gky661 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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