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5Y0D

Crystal Structure of the human nucleosome containing the H2B E76K mutant

Summary for 5Y0D
Entry DOI10.2210/pdb5y0d/pdb
DescriptorHistone H3.1, Histone H4, Histone H2A type 1-B/E, ... (8 entities in total)
Functional Keywordsdna binding, nucleus, histone fold, chromatin formation, nucleosome, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (Human)
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Total number of polymer chains10
Total formula weight202922.01
Authors
Kurumizaka, H.,Arimura, Y.,Fujita, R.,Noda, M. (deposition date: 2017-07-16, release date: 2018-07-18, Last modification date: 2023-11-22)
Primary citationArimura, Y.,Ikura, M.,Fujita, R.,Noda, M.,Kobayashi, W.,Horikoshi, N.,Sun, J.,Shi, L.,Kusakabe, M.,Harata, M.,Ohkawa, Y.,Tashiro, S.,Kimura, H.,Ikura, T.,Kurumizaka, H.
Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46:10007-10018, 2018
Cited by
PubMed: 30053102
DOI: 10.1093/nar/gky661
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.99 Å)
Structure validation

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