5XZV

Crystal structure of Rad53 1-466 in complex with AMP-PNP

Summary for 5XZV

Entry DOI	10.2210/pdb5xzv/pdb
Descriptor	Serine/threonine-protein kinase RAD53, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywords	serine/threonine-protein kinase, fha domain, checkpoint kinase, transferase
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular location	Nucleus : P22216
Total number of polymer chains	2
Total formula weight	106025.33
Authors	Weng, J.H.,Tsai, M.D. (deposition date: 2017-07-14, release date: 2017-10-11, Last modification date: 2024-03-27)
Primary citation	Chen, E.S.,Weng, J.H.,Chen, Y.H.,Wang, S.C.,Liu, X.X.,Huang, W.C.,Matsui, T.,Kawano, Y.,Liao, J.H.,Lim, L.H.,Bessho, Y.,Huang, K.F.,Wu, W.J.,Tsai, M.D. Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation Biochemistry, 56:5112-5124, 2017 Cited by PubMed: 28858528 DOI: 10.1021/acs.biochem.7b00689 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation