5X1O

PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study

Summary for 5X1O

• Entry DOI: 10.2210/pdb5x1o/pdb
• Descriptor: Fibroblast growth factor 2, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (3 entities in total)
• Functional Keywords: pi(4, 5)p2, fibroblast growth factor 2, protein binding
• Biological source: Homo sapiens (Human)
• Cellular location: Secreted: P09038
• Total number of polymer chains: 2
• Total formula weight: 33711.91

Authors

Tsao, Y.H. (deposition date: 2017-01-26, release date: 2018-03-07)

• Primary citation: Tsao, Y.H.; PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)