5WMN

Crystal Structure of HLA-B7 in complex with SPI, an influenza peptide

Summary for 5WMN

• Entry DOI: 10.2210/pdb5wmn/pdb
• Descriptor: HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, SPI peptide from Influenza A virus, ... (4 entities in total)
• Functional Keywords: hla, viral peptide, iav, ebv, cmv, crossreactivity, tcr, t cell, heterologous immunity, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 89861.26

Authors

Gras, S.,Rossjohn, J. (deposition date: 2017-07-30, release date: 2018-06-06, Last modification date: 2023-10-04)

• Primary citation: Rowntree, L.C.,Nguyen, T.H.O.,Halim, H.,Purcell, A.W.,Rossjohn, J.,Gras, S.,Kotsimbos, T.C.,Mifsud, N.A.; Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.; J. Immunol., 200:3993-4003, 2018; PubMed: 29735483; DOI: 10.4049/jimmunol.1800010

Experimental method

X-RAY DIFFRACTION (1.82 Å)