5WCG
SET and MYND Domain Containing protein 2
Summary for 5WCG
Entry DOI | 10.2210/pdb5wcg/pdb |
Descriptor | N-lysine methyltransferase SMYD2, ZINC ION, [3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanone, ... (7 entities in total) |
Functional Keywords | zinc finger, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm, cytosol : Q9NRG4 |
Total number of polymer chains | 1 |
Total formula weight | 50735.31 |
Authors | Dong, A.,Zeng, H.,Walker, J.R.,Hutch, A.,Seitova, A.,Tatlock, J.,Kumpf, R.,Owen, A.,Taylor, A.,Casimiro-Garcia, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2017-06-30, release date: 2017-08-02, Last modification date: 2023-10-04) |
Primary citation | Zeng, H.,Dong, A.,Walker, J.R.,Hutch, A.,Seitova, A.,Tatlock, J.,Kumpf, R.,Owen, A.,Taylor, A.,Casimiro-Garcia, A.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Wu, H. The crystal structure of SMYD2 in complex with compound MTF003 to be published, |
Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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