5W8T
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
Summary for 5W8T
| Entry DOI | 10.2210/pdb5w8t/pdb |
| Descriptor | Ubiquitin-like protein ISG15, ORF1ab, prop-2-en-1-amine, ... (6 entities in total) |
| Functional Keywords | signaling protein, hydrolase, papain-like protease, isg15 |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 90668.65 |
| Authors | Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.V.,Farhat, J.J.,Pegan, S.D. (deposition date: 2017-06-22, release date: 2017-09-27, Last modification date: 2020-04-29) |
| Primary citation | Daczkowski, C.M.,Goodwin, O.Y.,Dzimianski, J.V.,Farhat, J.J.,Pegan, S.D. Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus. J. Virol., 91:-, 2017 Cited by PubMed: 28931677DOI: 10.1128/JVI.01067-17 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.758 Å) |
Structure validation
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