5W3N

Molecular structure of FUS low sequence complexity domain protein fibrils

Summary for 5W3N

Entry DOI	10.2210/pdb5w3n/pdb
NMR Information	BMRB: 30304
Descriptor	RNA-binding protein FUS (1 entity in total)
Functional Keywords	low complexity sequence domain, rna transport, rna granule, intrinsically disordered protein, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	9
Total formula weight	223828.61
Authors	Murray, D.T.,Kato, M.,Lin, Y.,Thurber, K.,Hung, I.,McKnight, S.,Tycko, R. (deposition date: 2017-06-08, release date: 2017-09-27, Last modification date: 2023-06-14)
Primary citation	Murray, D.T.,Kato, M.,Lin, Y.,Thurber, K.R.,Hung, I.,McKnight, S.L.,Tycko, R. Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains. Cell, 171:615-627.e16, 2017 Cited by PubMed: 28942918 DOI: 10.1016/j.cell.2017.08.048 PDB entries with the same primary citation
Experimental method	SOLID-STATE NMR

Structure validation