5W0N

Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA

Summary for 5W0N

• Entry DOI: 10.2210/pdb5w0n/pdb
• Descriptor: Terminal uridylyltransferase 7, MAGNESIUM ION, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... (8 entities in total)
• Functional Keywords: terminal uridyltransferase, tutase, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : Q5VYS8
• Total number of polymer chains: 3
• Total formula weight: 143758.46

Authors

Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L. (deposition date: 2017-05-31, release date: 2017-06-28, Last modification date: 2023-10-04)

• Primary citation: Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L.; Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.; Nat. Struct. Mol. Biol., 24:658-665, 2017; PubMed: 28671666; DOI: 10.1038/nsmb.3428

Experimental method

X-RAY DIFFRACTION (2.497 Å)