5VKJ

Crystal structure of human CD22 Ig domains 1-3

Summary for 5VKJ

• Entry DOI: 10.2210/pdb5vkj/pdb
• Related: 5VKK 5VKM 5VL3
• EMDB information: 8704 8705
• Descriptor: B-cell receptor CD22, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total)
• Functional Keywords: siglec, sialic acid, carbohydrate binding protein, immune system
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 37939.49

Authors

Julien, J.P.,Ereno-Orbea, J.,Sicard, T. (deposition date: 2017-04-21, release date: 2017-10-04, Last modification date: 2024-04-03)

• Primary citation: Ereno-Orbea, J.,Sicard, T.,Cui, H.,Mazhab-Jafari, M.T.,Benlekbir, S.,Guarne, A.,Rubinstein, J.L.,Julien, J.P.; Molecular basis of human CD22 function and therapeutic targeting.; Nat Commun, 8:764-764, 2017; PubMed: 28970495; DOI: 10.1038/s41467-017-00836-6

Experimental method

X-RAY DIFFRACTION (2.12 Å)