5VEF

PAK4 kinase domain in complex with fasudil

Summary for 5VEF

Entry DOI	10.2210/pdb5vef/pdb
Related	5VED 5VEF
Descriptor	Serine/threonine-protein kinase PAK 4, 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, ACETATE ION, ... (4 entities in total)
Functional Keywords	kinase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	36376.15
Authors	Zhang, E.Y.,Ha, B.H.,Boggon, T.J. (deposition date: 2017-04-04, release date: 2017-10-18, Last modification date: 2023-10-04)
Primary citation	Zhang, E.Y.,Ha, B.H.,Boggon, T.J. PAK4 crystal structures suggest unusual kinase conformational movements. Biochim. Biophys. Acta, 1866:356-365, 2018 Cited by PubMed: 28993291 DOI: 10.1016/j.bbapap.2017.10.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.752 Å)

Structure validation