5VAI

Cryo-EM structure of the activated Glucagon-like peptide-1 receptor in complex with G protein

Summary for 5VAI

Entry DOI	10.2210/pdb5vai/pdb
EMDB information	8653
Descriptor	Uncharacterized protein, Glucagon-like peptide 1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total)
Functional Keywords	class b gpcr, glp-1, glp-1r, complex, signaling protein-hormone complex, signaling protein/hormone
Biological source	Oryctolagus cuniculus (Rabbit) More
Total number of polymer chains	6
Total formula weight	161760.52
Authors	Zhang, Y.,Sun, B.,Feng, D.,Hu, H.,Chu, M.,Qu, Q.,Tarrasch, J.T.,Li, S.,Kobilka, T.S.,Kobilka, B.K.,Skiniotis, G. (deposition date: 2017-03-27, release date: 2017-05-24, Last modification date: 2019-12-18)
Primary citation	Zhang, Y.,Sun, B.,Feng, D.,Hu, H.,Chu, M.,Qu, Q.,Tarrasch, J.T.,Li, S.,Sun Kobilka, T.,Kobilka, B.K.,Skiniotis, G. Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Nature, 546:248-253, 2017 Cited by PubMed: 28538729 DOI: 10.1038/nature22394 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.1 Å)

Structure validation