5V5P

Structure of NLS2R of influenza A virus nucleoprotein bound to importin alpha

Summary for 5V5P

• Entry DOI: 10.2210/pdb5v5p/pdb
• Related: 4ZDU 5V5O
• Descriptor: Importin subunit alpha-1, Nucleoprotein (3 entities in total)
• Functional Keywords: nuclear import, nls, viral protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 62647.91

Authors

Sankhala, R.S.,Lokareddy, R.K.,Cingolani, G. (deposition date: 2017-03-14, release date: 2018-03-14, Last modification date: 2023-10-04)

• Primary citation: Wu, W.,Sankhala, R.S.,Florio, T.J.,Zhou, L.,Nguyen, N.L.T.,Lokareddy, R.K.,Cingolani, G.,Pante, N.; Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.; Sci Rep, 7:11381-11381, 2017; PubMed: 28900157; DOI: 10.1038/s41598-017-11018-1

Experimental method

X-RAY DIFFRACTION (2.15 Å)