5V2N

Crystal Structure of APO Human SETD8

Summary for 5V2N

• Entry DOI: 10.2210/pdb5v2n/pdb
• Descriptor: N-lysine methyltransferase KMT5A, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: methyl transferase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 18687.02

Authors

Skene, R.J. (deposition date: 2017-03-05, release date: 2018-03-07, Last modification date: 2024-03-06)

• Primary citation: Chen, S.,Wiewiora, R.P.,Meng, F.,Babault, N.,Ma, A.,Yu, W.,Qian, K.,Hu, H.,Zou, H.,Wang, J.,Fan, S.,Blum, G.,Pittella-Silva, F.,Beauchamp, K.A.,Tempel, W.,Jiang, H.,Chen, K.,Skene, R.J.,Zheng, Y.G.,Brown, P.J.,Jin, J.,Luo, C.,Chodera, J.D.,Luo, M.; The dynamic conformational landscape of the protein methyltransferase SETD8.; Elife, 8:-, 2019; PubMed: 31081496; DOI: 10.7554/eLife.45403

Experimental method

X-RAY DIFFRACTION (2 Å)