5V0L

Crystal structure of the AHR-ARNT heterodimer in complex with the DRE

Summary for 5V0L

• Entry DOI: 10.2210/pdb5v0l/pdb
• Descriptor: Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor, DNA (5'-D(P*GP*GP*AP*TP*TP*GP*CP*GP*TP*GP*AP*GP*AP*AP*CP*TP*G)-3'), ... (6 entities in total)
• Functional Keywords: ahr, arnt, transcription factor, heterodimer, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 68323.52

Authors

Seok, S.-H.,Lee, W.,Jiang, L.,Bradfield, C.A.,Xing, Y. (deposition date: 2017-02-28, release date: 2017-04-19, Last modification date: 2023-10-04)

• Primary citation: Seok, S.H.,Lee, W.,Jiang, L.,Molugu, K.,Zheng, A.,Li, Y.,Park, S.,Bradfield, C.A.,Xing, Y.; Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.; Proc. Natl. Acad. Sci. U.S.A., 114:5431-5436, 2017; PubMed: 28396409; DOI: 10.1073/pnas.1617035114

Experimental method

X-RAY DIFFRACTION (4 Å)