5UQ2

Crystal structure of human Cdk2-Spy1 complex

Summary for 5UQ2

• Entry DOI: 10.2210/pdb5uq2/pdb
• Related: 5UQ1 5UQ3
• Descriptor: Cyclin-dependent kinase 2, Speedy protein A (3 entities in total)
• Functional Keywords: phosphotransferase, protein kinase, cell cycle regulation, transferase-cell cycle complex, transferase/cell cycle
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941; Nucleus : Q5MJ70
• Total number of polymer chains: 2
• Total formula weight: 53622.05

Authors

McGrath, D.A.,Tripathi, S.M.,Rubin, S.M. (deposition date: 2017-02-06, release date: 2017-07-05, Last modification date: 2017-08-09)

• Primary citation: McGrath, D.A.,Fifield, B.A.,Marceau, A.H.,Tripathi, S.,Porter, L.A.,Rubin, S.M.; Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.; EMBO J., 36:2251-2262, 2017; PubMed: 28666995; DOI: 10.15252/embj.201796905

Experimental method

X-RAY DIFFRACTION (2.7 Å)