5UGW
STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN
Summary for 5UGW
| Entry DOI | 10.2210/pdb5ugw/pdb |
| Related | 3DU6 |
| Descriptor | Telomerase reverse transcriptase, GLUTATHIONE (3 entities in total) |
| Functional Keywords | telomerase, reverse transcriptase, transferase, thumb domain |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 20107.59 |
| Authors | Skordalakes, E.,Hoffman, H. (deposition date: 2017-01-10, release date: 2017-02-08, Last modification date: 2024-03-06) |
| Primary citation | Hoffman, H.,Rice, C.,Skordalakes, E. Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes. J. Biol. Chem., 292:4593-4601, 2017 Cited by PubMed: 28154186DOI: 10.1074/jbc.M116.771204 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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