5UFS

X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment

Summary for 5UFS

Entry DOI	10.2210/pdb5ufs/pdb
Descriptor	Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide, ... (4 entities in total)
Functional Keywords	nuclear receptors, glucocorticoid receptor, ligand binding domain, hormone receptor
Biological source	unidentified More
Total number of polymer chains	4
Total formula weight	60252.18
Authors	Weikum, E.R.,Ortlund, E.A. (deposition date: 2017-01-05, release date: 2017-04-26, Last modification date: 2023-10-04)
Primary citation	Weikum, E.R.,Okafor, C.D.,D'Agostino, E.H.,Colucci, J.K.,Ortlund, E.A. Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner. Mol. Pharmacol., 92:12-21, 2017 Cited by PubMed: 28396564 DOI: 10.1124/mol.117.108506 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.118 Å)

Structure validation