5UAT
Structure of human PYCR-1 complexed with NADPH
Summary for 5UAT
| Entry DOI | 10.2210/pdb5uat/pdb |
| Related | 5UAU 5UAV 5UAW 5UAX |
| Descriptor | Pyrroline-5-carboxylate reductase 1, mitochondrial, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
| Functional Keywords | amino-acid biosynthesis, oxidoreductase, proline biosynthesis |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 5 |
| Total formula weight | 172196.99 |
| Authors | Tanner, J.J. (deposition date: 2016-12-20, release date: 2017-03-15, Last modification date: 2023-10-04) |
| Primary citation | Christensen, E.M.,Patel, S.M.,Korasick, D.A.,Campbell, A.C.,Krause, K.L.,Becker, D.F.,Tanner, J.J. Resolving the cofactor-binding site in the proline biosynthetic enzyme human pyrroline-5-carboxylate reductase 1. J. Biol. Chem., 292:7233-7243, 2017 Cited by PubMed: 28258219DOI: 10.1074/jbc.M117.780288 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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