5U98

The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01

Summary for 5U98

• Entry DOI: 10.2210/pdb5u98/pdb
• Descriptor: HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, VAL-THR-THR-ASP-ILE-GLN-VAL-LYS-VAL, ... (5 entities in total)
• Functional Keywords: mhc, antigen presenting cell, t-cell receptor, human leukocyte antigen, drug hypersensitivity, abacavir hypersensitivity, repertoire-altering small molecule, immune response, immunoglobulin-like beta-sandwich, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 89810.05

Authors

Ostrov, D.A.,Bracey, A.W.,Pompeu, Y.A.,Jakoncic, J.,Buus, S.,Buus, A.S.,Schutte, R.J. (deposition date: 2016-12-15, release date: 2017-07-19, Last modification date: 2023-10-04)

• Primary citation: Yerly, D.,Pompeu, Y.A.,Schutte, R.J.,Eriksson, K.K.,Strhyn, A.,Bracey, A.W.,Buus, S.,Ostrov, D.A.; Structural Elements Recognized by Abacavir-Induced T Cells.; Int J Mol Sci, 18:-, 2017; PubMed: 28686208; DOI: 10.3390/ijms18071464

Experimental method

X-RAY DIFFRACTION (2 Å)