5U8S

Structure of eukaryotic CMG helicase at a replication fork

Summary for 5U8S

• Entry DOI: 10.2210/pdb5u8s/pdb
• EMDB information: 8518
• Descriptor: DNA replication complex GINS protein PSF1, DNA replication licensing factor MCM4, Minichromosome maintenance protein 5, ... (14 entities in total)
• Functional Keywords: cmg helicase, replisome, origin initiation, dna polymerase, dna replication, replication
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 13
• Total formula weight: 799671.57

Authors

Li, H.,Li, B.,Georgescu, R.,Yuan, Z.,Santos, R.,Sun, J.,Zhang, D.,Yurieva, O.,O'Donnell, M.E. (deposition date: 2016-12-14, release date: 2017-01-25, Last modification date: 2020-01-01)

• Primary citation: Georgescu, R.,Yuan, Z.,Bai, L.,de Luna Almeida Santos, R.,Sun, J.,Zhang, D.,Yurieva, O.,Li, H.,O'Donnell, M.E.; Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.; Proc. Natl. Acad. Sci. U.S.A., 114:E697-E706, 2017; PubMed: 28096349; DOI: 10.1073/pnas.1620500114

Experimental method

ELECTRON MICROSCOPY (6.101 Å)