5U6P

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Summary for 5U6P

• Entry DOI: 10.2210/pdb5u6p/pdb
• Related: 5U6O
• EMDB information: 8511 8512
• Descriptor: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: pacemaker ion channel, transport protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : O60741
• Total number of polymer chains: 8
• Total formula weight: 306431.78

Authors

Lee, C.-H.,MacKinnon, R. (deposition date: 2016-12-08, release date: 2017-01-25, Last modification date: 2024-03-13)

• Primary citation: Lee, C.H.,MacKinnon, R.; Structures of the Human HCN1 Hyperpolarization-Activated Channel.; Cell, 168:111-120.e11, 2017; PubMed: 28086084; DOI: 10.1016/j.cell.2016.12.023

Experimental method

ELECTRON MICROSCOPY (3.51 Å)