5TRM

Crystal structure of human GCN5 histone acetyltransferase domain

Summary for 5TRM

• Entry DOI: 10.2210/pdb5trm/pdb
• Related: 5TRL
• Descriptor: Histone acetyltransferase KAT2A (1 entity in total)
• Functional Keywords: apo, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q92830
• Total number of polymer chains: 24
• Total formula weight: 465759.84

Authors

Guo, Y.R.,Tao, Y.J. (deposition date: 2016-10-26, release date: 2017-12-06, Last modification date: 2023-10-04)

• Primary citation: Wang, Y.,Guo, Y.R.,Liu, K.,Yin, Z.,Liu, R.,Xia, Y.,Tan, L.,Yang, P.,Lee, J.H.,Li, X.J.,Hawke, D.,Zheng, Y.,Qian, X.,Lyu, J.,He, J.,Xing, D.,Tao, Y.J.,Lu, Z.; KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.; Nature, 552:273-277, 2017; PubMed: 29211711; DOI: 10.1038/nature25003

Experimental method

X-RAY DIFFRACTION (2.9 Å)