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5TOJ

Crystal structure of the RSV F glycoprotein in complex with the neutralizing single-domain antibody F-VHH-4

Summary for 5TOJ
Entry DOI10.2210/pdb5toj/pdb
Related5TOK
DescriptorFusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-4, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordsfusion, nanobody, immunoglobulin fold, complex, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman respiratory syncytial virus
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Total number of polymer chains6
Total formula weight227109.53
Authors
Gilman, M.S.A.,Kabeche, S.C.,McLellan, J.S. (deposition date: 2016-10-17, release date: 2017-02-22, Last modification date: 2023-10-04)
Primary citationRossey, I.,Gilman, M.S.,Kabeche, S.C.,Sedeyn, K.,Wrapp, D.,Kanekiyo, M.,Chen, M.,Mas, V.,Spitaels, J.,Melero, J.A.,Graham, B.S.,Schepens, B.,McLellan, J.S.,Saelens, X.
Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8:14158-14158, 2017
Cited by
PubMed: 28194013
DOI: 10.1038/ncomms14158
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.3 Å)
Structure validation

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