5TOA

Crystal Structure of ER beta bound to Estradiol

Summary for 5TOA

Entry DOI	10.2210/pdb5toa/pdb
Descriptor	Estrogen receptor beta, ESTRADIOL (3 entities in total)
Functional Keywords	estrogen receptor, estradiol, helix 12, agonist, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	56603.23
Authors	Textor, L.,Nascimento, A.S.,Polikarpov, I. (deposition date: 2016-10-17, release date: 2017-06-28, Last modification date: 2023-10-04)
Primary citation	Souza, P.C.T.,Textor, L.C.,Melo, D.C.,Nascimento, A.S.,Skaf, M.S.,Polikarpov, I. An alternative conformation of ER beta bound to estradiol reveals H12 in a stable antagonist position. Sci Rep, 7:3509-3509, 2017 Cited by PubMed: 28615710 DOI: 10.1038/s41598-017-03774-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation