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5TH2

Cetuximab Fab in complex with L5Q meditope variant

Summary for 5TH2
Entry DOI10.2210/pdb5th2/pdb
Related4GW1 4IWE 5ETU 5EUK 5F88 5FF6 5I2I 5IOP 5IR1 5ITF 5IV2 5IVZ 5T1K 5T1L 5T1M
Descriptorcetuximab Fab, light chain, cetuximab Fab, heavy chain, L5Q meditope, ... (5 entities in total)
Functional Keywordsantibody, anti-egfr, immune system
Biological sourceMus musculus, Homo sapiens
More
Total number of polymer chains6
Total formula weight97286.79
Authors
Bzymek, K.P.,Williams, J.C. (deposition date: 2016-09-28, release date: 2016-10-26, Last modification date: 2023-10-04)
Primary citationBzymek, K.P.,Avery, K.A.,Ma, Y.,Horne, D.A.,Williams, J.C.
Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Acta Crystallogr F Struct Biol Commun, 72:820-830, 2016
Cited by
PubMed: 27834791
DOI: 10.1107/S2053230X16016149
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.84 Å)
Structure validation

217705

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