5TBK

Crystal structure of human importin a3 bound to RCC1

Summary for 5TBK

• Entry DOI: 10.2210/pdb5tbk/pdb
• Related: 4PVZ 5T94
• Descriptor: Importin subunit alpha-3, Regulator of chromosome condensation (2 entities in total)
• Functional Keywords: nuclear import, importin alpha, rcc1 like domain (rld), nls, protein transport - nuclear protein complex, protein transport / nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 16
• Total formula weight: 823730.69

Authors

Sankhala, R.S.,Lokareddy, R.K.,Pumroy, R.A.,Cingolani, G. (deposition date: 2016-09-12, release date: 2017-09-13, Last modification date: 2023-10-04)

• Primary citation: Sankhala, R.S.,Lokareddy, R.K.,Begum, S.,Pumroy, R.A.,Gillilan, R.E.,Cingolani, G.; Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1.; Nat Commun, 8:979-979, 2017; PubMed: 29042532; DOI: 10.1038/s41467-017-01057-7

Experimental method

X-RAY DIFFRACTION (3.45 Å)