5T7R
A6-A11 trans-dicarba human insulin
Summary for 5T7R
Entry DOI | 10.2210/pdb5t7r/pdb |
Descriptor | Insulin A chain, Insulin B chain (3 entities in total) |
Functional Keywords | insulin dicarba bond, hormone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 11563.15 |
Authors | Menting, J.G.,Lawrence, M.C.,Robinson, A.J.,Forbes, B.E. (deposition date: 2016-09-05, release date: 2017-12-06, Last modification date: 2019-06-19) |
Primary citation | van Lierop, B.,Ong, S.C.,Belgi, A.,Delaine, C.,Andrikopoulos, S.,Haworth, N.L.,Menting, J.G.,Lawrence, M.C.,Robinson, A.J.,Forbes, B.E. Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity. Sci Rep, 7:17239-17239, 2017 Cited by PubMed: 29222417DOI: 10.1038/s41598-017-16876-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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